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Pramlintide
SymlinMetabolic/WeightEvidence grade
AFDA-approved Rx (labeled use)
Cardiovascular · 0–5 · separate axis
3
Read first · not dosing instructions
Educational and research reference only. Not medical advice, not a recommendation, and not dosing instructions for any person. Figures are reported from the cited source and may be wrong or out of date. Research peptides are not approved for human use. Adults 18+. Consult a licensed physician before any decision about your health.
PurposeMetabolic / Diabetes
MechanismAmylin analog: slows gastric emptying, suppresses glucagon, promotes satiety
EffectsMore satiety + slower digestion; improves post-meal blood sugar
DosingT1D: start 15 mcg pre-meals; titrate; T2D: start 60 mcg pre-meals → 120 mcg
Bottom lineStrongest data when used for its labeled indication under clinician guidance.
Batches on filenone
No tested batches on file.
Cautions & interactions
Hypoglycemia risk (requires insulin dose reduction); nausea; careful glucose monitoring
Requires mealtime insulin dose reduction (hypoglycemia risk); delays gastric emptying—separate timing for oral meds that need rapid absorption.
CV 3 of 5 — Improves post-meal glucose and satiety; indirect CV benefit via glycemic control (less direct outcomes data).