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MGF
Mechano Growth Factor, researchMuscle/PerformanceEvidence grade
DResearch/compounded/adjunct (no established FDA indication)
Cardiovascular · 0–5 · separate axis
1
Read first · not dosing instructions
Educational and research reference only. Not medical advice, not a recommendation, and not dosing instructions for any person. Figures are reported from the cited source and may be wrong or out of date. Research peptides are not approved for human use. Adults 18+. Consult a licensed physician before any decision about your health.
PurposeMuscle / Performance
MechanismSplice variant of IGF-1 expressed in muscle after mechanical loading; studied for satellite-cell activation
EffectsStudied for local repair signalling in muscle after damage
DosingNo human dose established.
Bottom linePopular in research/compounding; human safety/benefit not well-established.
Protocols · as published1 sourced
Community protocol — not clinically establishedCommunity guide
RouteIntramuscular into the trained muscle
FrequencyImmediately post-workout
Starting100-200 mcg IM post-workout
EscalationNot stated
Target100-200 mcg IM
Cycle4-6 weeks on, 4-6 weeks off
WhereLocal IM into the trained muscle.
"Large-scale human clinical trials for exogenous MGF injection are lacking."
Sourcepeptidewiki.co ↗
Batches on filenone
No tested batches on file.
Cautions & interactions
Not FDA-approved; avoid self-administration; unverified sourcing and purity
No well-established interaction profile for non-approved peptides; avoid combining multiple research compounds; discuss meds with clinician.
CV 1 of 5 — No solid direct cardiovascular outcomes evidence; any benefit is indirect or unproven.