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Icatibant
FirazyrImmune/Anti-infEvidence grade
AFDA-approved Rx (labeled use)
Cardiovascular · 0–5 · separate axis
1
Read first · not dosing instructions
Educational and research reference only. Not medical advice, not a recommendation, and not dosing instructions for any person. Figures are reported from the cited source and may be wrong or out of date. Research peptides are not approved for human use. Adults 18+. Consult a licensed physician before any decision about your health.
PurposeImmune / Inflammatory
MechanismBradykinin B2 receptor antagonist; blocks the mediator driving hereditary angioedema attacks
EffectsTreats an attack in progress rather than preventing one
Dosing30 mg SC as a single dose; may repeat per prescribing information
Bottom lineStrongest data when used for its labeled indication under clinician guidance.
Batches on filenone
No tested batches on file.
Cautions & interactions
Injection-site reactions are near-universal; laryngeal attacks still require emergency care
May reduce the antihypertensive effect of ACE inhibitors; discuss with the prescribing clinician.
CV 1 of 5 — No adverse cardiovascular signal at labelled use; bradykinin blockade is theoretically relevant to ACE-inhibitor effects.