← The library
DSIP
researchSleepEvidence grade
DResearch/compounded/adjunct (no established FDA indication)
Cardiovascular · 0–5 · separate axis
1
Read first · not dosing instructions
Educational and research reference only. Not medical advice, not a recommendation, and not dosing instructions for any person. Figures are reported from the cited source and may be wrong or out of date. Research peptides are not approved for human use. Adults 18+. Consult a licensed physician before any decision about your health.
PurposeSleep
MechanismDelta sleep–inducing peptide (experimental)
EffectsDelta sleep–inducing peptide (experimental)
DosingNo human dose established.
Bottom linePopular in research/compounding; human safety/benefit not well-established.
Protocols · as published2 sourced
Clinical trialChronic insomnia (Schneider-Helmert, 1981, n=6)
RouteIntravenous
FrequencyAcute
Starting25 nmol/kg IV
EscalationNone
TargetAcute dose; longer, less-interrupted sleep, no daytime sedation
A 1987 short-term study found differences from placebo did not reach clinical significance.
SourcesPubMed 7028502 ↗ · PubMed 3583493 (1987) ↗
Community protocol — not clinically establishedCommunity guide
RouteSubcutaneous
FrequencyOnce, in the evening, 1-3 hours before intended sleep
Starting100-200 mcg SC ("most common community range"); no formal escalation
EscalationNone. Higher tier 200-300 mcg "used in some research write-ups".
Target100-300 mcg SC evening
CycleShort 5-7 nights; standard 4 weeks; extended 6-8 weeks
No SC human data.
Batches on filenone
No tested batches on file.
Cautions & interactions
Not FDA-approved; limited evidence
No well-established interaction profile for non-approved peptides; avoid combining multiple research compounds; discuss meds with clinician.
CV 1 of 5 — No solid direct cardiovascular outcomes evidence; any benefit is indirect or unproven.