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Degarelix
FirmagonSexual HealthEvidence grade
AFDA-approved Rx (labeled use)
Cardiovascular · 0–5 · separate axis
2
Read first · not dosing instructions
Educational and research reference only. Not medical advice, not a recommendation, and not dosing instructions for any person. Figures are reported from the cited source and may be wrong or out of date. Research peptides are not approved for human use. Adults 18+. Consult a licensed physician before any decision about your health.
PurposeReproductive axis
MechanismGnRH receptor antagonist; suppresses testosterone immediately with no initial flare
EffectsBlocks the receptor directly, avoiding the testosterone surge that agonists cause
Dosing240 mg SC loading dose, then 80 mg SC every 28 days
Bottom lineStrongest data when used for its labeled indication under clinician guidance.
Batches on filenone
No tested batches on file.
Cautions & interactions
Injection-site reactions are common; hot flushes; transaminase elevations
Additive with other hormone therapies; may prolong QT.
CV 2 of 5 — Some comparative data suggest fewer cardiovascular events than GnRH agonists in men with existing cardiac disease.