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Glutathione
GSH, reduced L-glutathioneSkin/HairEvidence grade
CMixed/unclear regulatory status
Cardiovascular · 0–5 · separate axis
1
PurposeAntioxidant / Skin
MechanismEndogenous tripeptide antioxidant; injected forms are marketed for skin lightening on the premise of shifting melanin synthesis from eumelanin toward pheomelanin.
EffectsWidely used for skin brightening and marketed for detoxification. No published clinical trial has evaluated injectable glutathione for skin lightening.
DosingNo human dose established.
Bottom lineHeavily marketed, entirely untrialled by injection, and carrying documented serious harms.
Batches on filenone
No tested batches on file.
Read with
The library records no pairings for this entry.
Cautions & interactions
The FDA has not approved glutathione for skin lightening and has warned against intravenous use for that purpose. Reported harms include anaphylaxis, hepatotoxicity, renal and neurological toxicity, and Stevens-Johnson syndrome. Shifting melanin type may raise sun-induced skin-cancer risk in previously protected skin.
No systematic interaction data for injectable use.
CV 1 of 5 — No cardiovascular outcomes data. Infusion reactions include chest tightness.